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Malaria is a disease caused by a parasite that can infect people's red blood cells. The parasite is spread to people by the bites of infected mosquitoes.
Most malaria infections cause flu-like symptoms (such as high fever, chills, muscle pain, and diarrhea) that come and go in cycles. A serious form of malaria can cause serious heart, lung, kidney, and brain problems, or death.
Many malaria cases occur in people who have traveled to developing countries (especially Africa). A person can reduce the risk of malaria by taking steps to prevent mosquito bites and by taking preventive medication that reduces the risk of infection in case the person is bitten by an infected mosquito. Medications are also used to treat malaria.
Malaria can persist for years. A person may have repeated cycles of illness.
Doxycycline is an antibiotic that prevents the development of parasites in the blood that cause malaria. Doxycycline does not destroy the Plasmodium (P.)vivaxand/or P. ovale parasites that may remain in the liver.
You take doxycycline as a tablet (orally).
To prevent malaria, you take doxycycline 1 to 2 days before you travel to an area where malaria is present, daily while you are in the area, and daily for 4 weeks after you leave the area.
To treat malaria, doxycycline is usually used along with quinine sulfate for 7 days.
Why It Is Used
Doxycycline is used to prevent malaria:
* In chloroquine-resistant areas (where chloroquine is no longer effective against the parasite) when you cannot take mefloquine (for example, because of side effects).
* If you will be traveling in certain areas of Thailand.
How Well It Works
Doxycycline is effective in the prevention of malaria.
Side Effects
Side effects of doxycycline are common and include:
* Stomach upset and nausea.
* Diarrhea.
* Vaginal yeast infection (yeast vaginitis).
* Sensitivity of the skin to sun exposure (severe sunburn) and of the eyes to light (photosensitivity).
Side effects may be relieved if you take the medicine with meals.
What To Think About
Do not use doxycycline if you are pregnant. It is not used for children younger than age 9 because it may stain their teeth. |